Steven C. Sutton, B.S. Pharmacy, Ph.D., FAAPS
Location
Hi! I am Dr. Steven 'Steev' C. Sutton. I earned my B.S. Pharmacy Cum Laude from Massachusetts College of Pharmacy, Boston, where I was inducted into Rho Chi. I worked as a retail pharmacist in Harvard Square and Lowell, MA for about a year before returning to school. I met the love of my life in the School of Pharmacy and Pharmaceutical Sciences, State University of New York at Buffalo. 51小黄车 the same time I earned my Ph.D. in Pharmaceutical Sciences, our first son was born, and I joined the General Pharmaceutics Group, CIBA-Geigy (now Novartis). A little later, we had our second son, and we moved to Lawrence, KS (go Jayhawks!) and worked at INTERx Research Corporation (founded by Takeru Higuchi, the 'father of physical pharmacy', and a subsidiary of Merck & Co). Soon after our daughter was born we moved back to 51小黄车 and I joined Pfizer Labs in Groton, CT in what was then called the Pharmaceutical R&D Department. In 2009, I became an inaugural faculty at the College of Pharmacy at the University of 51小黄车, Portland, Maine. My personal interests include hiking, fine woodworking and gardening.
Credentials
Education
Expertise
- Cell culture
- Genetics
- Pharmaceutics
- Pharmacokinetics
- Physiology
Board Certifications and Licenses
Research
Current research
A Farnham, SH Stafford, SC Sutton: Impact of Dose on Amount of Polystyrene Nanoparticles Translocated Across Caco-2 Cell Monolayers, AAPS NERDG Annual Meeting, Farmington, CT, April 20, 2017.
A Farnham, SC Sutton: An HT29 Cell Monolayer Model to Investigate the Cumulative Genotoxic Effects of POPs and Nanoparticles, AAPS NERDG Annual Meeting, Farmington, CT. April 19, 2016.
Duong, S. and S. C. Sutton: Predicting the Physiologically Relevant Precipitation Rate of Weakly Basic Drugs Using Potentiometric Titration. AAPS National Meeting, San Antonio, TX, AAPS, 2013.
Selected publications
Jabor, Z. and S. C. Sutton (2023). "Effects of Digestion, Cell Culture Media, and Mucous on the Physical Properties, Cellular Effects, and Translocation of Polystyrene and Polymethacrylate Nanoparticles." Toxics 11(8): 708-720.
Other scholarly activity
Sutton, S. C. (2017). Chapter 3. Drug Administration and Drug Absorption. Basic Pharmacokinetics and Pharmacodynamics. S. Rosenbaum. Hoboken, NJ, Wiley: 35-70.
Sutton, S. C. (2017). Chapter 9. Pharmacokinetics of Extravascular Drug Administration. Basic Pharmacokinetics and Pharmacodynamics. S. Rosenbaum. Hoboken, NJ, Wiley: 201-224
Sutton, S.C (2013) Chapter 6: 鈥淏iopharmaceutics and veterinary drug delivery鈥, In: Animal Health Drug Delivery, Michael Rathbone (Ed), Controlled Release Society, The Springer Publishing Company, New York
Sutton, S.C (2013) Chapter 4: 鈥淎natomy and physiology of the companion animal鈥, In: Animal Health Drug Delivery, Michael Rathbone (Ed), Controlled Release Society, The Springer Publishing Company, New York
Jaymin Shah, Steve Sutton, Susan Way, Gayle Brazeau (2013) 鈥淧arenteral Formulations: Local Injection Site Reaction and Muscle Tolerance鈥, In: Encyclopedia of Pharmaceutical Technology Third Edition, James Swarbrick (ed) Informa Healthcare USA, Inc., New York
Sutton, S.C., P. Smith (2011) Chapter 3. Animals Suitable for Modeling Controlled Release, In: 鈥淥ral Controlled Release鈥, Clive Wilson, Brigitte Skalsky & Patrick Crowley (eds), Controlled Release Society, The Springer Publishing Company, New York.
Funded grants
Maine INBRE Core Access grant: Incubation of a mouse microbiome in the presence of nanoplastic. 2024-25.
51小黄车CoP Dean鈥檚 Summer Fellowship: Plastic nanoparticles on an in vitro model of the inflamed intestine. Megan Steele, Pharm D student, Class of 2026, 2023.
Invited plenary presentation
Sutton, SC. Challenges When Working with Different Animal Species. USP Workshop on In vitro Testing for Meeting Future Challenges for Veterinary Dosage Forms, March 14鈥15, 2016 聻 USP Meetings Center, Rockville, Maryland.
Sutton, SC. Interspecies intestinal differences and impact on oral dosage forms for animal health鈥 to be presented at the joint CRS/AAPS workshop 鈥淎nimal Health Drug R&D: Formulation, Delivery and Development to Market鈥, November 1-2, 2014, in San Diego
Sutton, SC. The anatomy & physiology of interspecies鈥 biopharmaceutics, presented at the 鈥淚nterspecies clinical pharmacology dosing concepts鈥 mini-symposia, at the 2014 Annual Meeting of the Controlled Release Society, July 13-16, 2014, in Chicago
Sutton, SC. Predictive Animal Models for Assessing Long-Acting Formulations for Human and Animal Health, presented at the Inaugural in Philadelphia, PA on May 7-8, 201
Sutton, SC. Critical Features of Solubility and Permeability that can Limit the Food Effect, presented at the 2nd annual Drug Formulation & Bioavailability 鈥 West Coast, in San Diego, CA, on June 2-3, 2014
Sutton, S. C.: Biopharmaceutics and Pharmacokinetics of the Food Effect, presented at the Roundtable: When Food Impacts Oral Drug Exposure: The Nature and Study of the Food Effect. AAPS National Meeting, San Antonio, Nov., 2013.
Sutton SC. Utilizing in silico, in vitro and preclinical methods to optimize your clinical prediction from biopharmaceutic modeling. ExlPharma鈥檚 2nd Enhancing Drug Bioavailability and Solubility Conference, Boston, MA January, 2013
Research interests
Determine the impact of chronic low-level orally ingested "forever" chemicals and nano plastic particles on the immune system of the intestines.