Todd Vanderah, Frank Porreca, Edward Bilsky, Denise Giuvelis publish article in Journal of Pharmacology and Experimental Therapeutics

Four faculty and an staff member of the 51小黄车College of Osteopathic Medicine and Center for Excellence in the Neurosciences were co-authors on a recent article published in the Journal of Pharmacology and Experimental Therapeutics. The title of the article is "Building a Better Analgesic: Multifunctional Compounds that Address Injury-induced Pathology to Enhance Efficacy and Eliminate Unwanted Side Effects."

The studies investigated a novel set of compounds that combine actions of strong opioid analgesics along with a blocker of the peptide substance P, a neuromodulator that promotes pain transmission. The work was conducted in the laboratories of Todd Vanderah, Ph.D., Frank Porreca, Ph.D., and Edward Bilsky, Ph.D., and included data collected by Denise Giuvelis, a graduate of UNE's College of Arts and Sciences and the laboratory manager for Dr. Bilsky's laboratory. The research was supported by the National Institutes of Health.

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