Steev Sutton publishes in 'Molecular Pharmaceutics' journal

Steev Sutton, Ph.D., chair of the Department of Pharmaceutical Sciences, recently co-authored an article titled, "Solid Nanocrystalline Dispersions of Ziprasidone with Enhanced Bioavailability in the Fasted State" in the journal Molecular Pharmaceutics.

Ziprasidone [Geodon (c) is an atypical antipsychotic that requires the patient to take this medicine with at least 500 calories for optimal absorption and, therefore, efficacy. This publication outlined the research and development that went into creating a reduced food effect formulation, which is expected to result in an optimal efficacy without regard to meals.

Citation:
Aarde, S. M.; Angrish, D.; Barlow, D. J.; Wright, M. J.; Vanderwater, S. A.; Creehan, K. M.; Houseknecht, K. L.; Dickerson, T. J.; Taffe, M. A. Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats. Addict. Biol., 2013, in press.

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